2025-07-12_00000149|medium|9IQP

Crystal structure of the Wuhan SARS-CoV-2 Spike RBD (319-541) complexed with 1p1B10 nanobody; X-ray diffraction 1.55Å
Protein #1 235 residues (83% resolved)

RVQPTESIVRFPNITNLCPFGEVFNATRFASVYAWNRKRISNCVADYSVLYNSASFSTFKCYGVSPTKLNDLCFTNVYADSFVIRGDEVRQIAPGQTGKIADYNYKLPDDFTGCVIAWNSNNLDSKVGGNYNYLYRLFRKSNLKPFERDISTEIYQAGSTPCNGVEGFNCYFPLQSYGFQPTNGVGYQPYRVVVLSFELLHAPATVCGPKKSTNLVKNKCVNFGSHHHHHHHHHH

RVQPTESIVRFPNITNLCPFGEVFNATRFASVYAWNRKRISNCVADYSVLYNSASFSTFKCYGVSPTKLNDLCFTNVYADSFVIRGDEVRQIAPGQTGKIADYNYKLPDDFTGCVIAWNSNNLDSKVGGNYNYLYRLFRKSNLKPFERDISTEIYQAGSTPCNGVEGFNCYFPLQSYGFQPTNGVGYQPYRVVVLSFELLHAPATVCGPKKSTNLVKNKCVNFGSHHHHHHHHHH
Protein #2 150 residues (83% resolved)

QVQLQESGGGSVQAGGSLRLSCTPSGFTVHDSDMGWYRVKPGNECELVTTLFGDGDTYYADSVKDRFIISQDNAKNTVYLQMNNLKPEDTAKYHCVARGVGVYGMHWFCGEYNFAGQGTQVTVSSAAAEQKLISEEDLNGAAHHHHHHGS

QVQLQESGGGSVQAGGSLRLSCTPSGFTVHDSDMGWYRVKPGNECELVTTLFGDGDTYYADSVKDRFIISQDNAKNTVYLQMNNLKPEDTAKYHCVARGVGVYGMHWFCGEYNFAGQGTQVTVSSAAAEQKLISEEDLNGAAHHHHHHGS
Non polymer #3 NA

InChI=1S/Na/q+1

[Na+]
Non polymer #4 NAG

InChI=1S/C8H15NO6/c1-3(11)9-5-7(13)6(12)4(2-10)15-8(5)14/h4-8,10,12-14H,2H2,1H3,(H,9,11)/t4-,5-,6-,7-,8-/m1/s1

CC(=O)N[C@@H]1[C@H]([C@@H]([C@H](O[C@H]1O)CO)O)O
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