2025-07-12_00000070|ligand|9FZ9

Glycoside Hydrolase Family 157 from Labilibaculum antarcticum, wild type SeMet derivative (LaGH157); X-ray diffraction 2.44Å

Protein #1 537 residues (98% resolved)

Raw Sequence ...

(MSE)QSKTKIELKDNWYHLDGEKYFIKAIGYEIGARPGQAPYEDERKDELEL(MSE)KFDLENIKEGGYNTIRTWSQYSENQLKLVQESGLKLI(MSE)GIDIKPEEDYGDPEFVKDSEIELKRVLNYAKKYDCIITYLVINEPQTDHIHSVTGKAFVDL(MSE)NTLINIIHKGHPGIPVTLSANA(MSE)ISDY(MSE)DESIFDVYAYNCYDHNEGQTAT(MSE)GFKDYIKGLNELNGLDKPFITTEFGYSVSPEGGNGQYGSNTLKQQSDGLISNYRDLIDAGAVG(MSE)CPFYYADGWWKGGEKSDHSLNQPEEWFGFWGYSDLNDKYGTPRPVWFA(MSE)RDY(MSE)KGLIISPKNKSIHTNTKIPLELYNDKDVKKVVVKFRDKVIYSKNITSEGY(MSE)ADELTIDPVGIED(MSE)ELAFEFYDSDNKIIKNESINILASKTAFELPELTIEVTPEKDLNEGKIASIKTKIETSENFTLLDDLKISYNTHLGWAIGSQASVSISDQLDKKIITSENFFNIPDNCWVVNASAGISVRYGKFTFKIHDQKIIYRGDWAKEVGRKLEHHHHHH

Canonical Sequence ...

MQSKTKIELKDNWYHLDGEKYFIKAIGYEIGARPGQAPYEDERKDELELMKFDLENIKEGGYNTIRTWSQYSENQLKLVQESGLKLIMGIDIKPEEDYGDPEFVKDSEIELKRVLNYAKKYDCIITYLVINEPQTDHIHSVTGKAFVDLMNTLINIIHKGHPGIPVTLSANAMISDYMDESIFDVYAYNCYDHNEGQTATMGFKDYIKGLNELNGLDKPFITTEFGYSVSPEGGNGQYGSNTLKQQSDGLISNYRDLIDAGAVGMCPFYYADGWWKGGEKSDHSLNQPEEWFGFWGYSDLNDKYGTPRPVWFAMRDYMKGLIISPKNKSIHTNTKIPLELYNDKDVKKVVVKFRDKVIYSKNITSEGYMADELTIDPVGIEDMELAFEFYDSDNKIIKNESINILASKTAFELPELTIEVTPEKDLNEGKIASIKTKIETSENFTLLDDLKISYNTHLGWAIGSQASVSISDQLDKKIITSENFFNIPDNCWVVNASAGISVRYGKFTFKIHDQKIIYRGDWAKEVGRKLEHHHHHH

Non polymer #2 ACT

InChI=1S/C2H4O2/c1-2(3)4/h1H3,(H,3,4)/p-1

SMILES: CC(=O)[O-]

CC(=O)[O-]

Non polymer #3 MLA

InChI=1S/C3H4O4/c4-2(5)1-3(6)7/h1H2,(H,4,5)(H,6,7)

SMILES: C(C(=O)O)C(=O)O

C(C(=O)O)C(=O)O

Biounit #1 monomer

Biounit #2 monomer

Biounit #3 monomer

Biounit #4 monomer

Reference