2025-07-05_00000208|hard|9KBI

The structure of B19V NS1_2-570/dsDNA/AMPPNP; Electron microscopy 3.43Å

Protein #1 569 residues (51% resolved)

Raw Sequence ...

ELFRGVLQVSSNVLDCANDNWWCSLLDLDTSDWEPLTHTNRLMAIYLSSVASKLDFTGGPLAGCLYFFQVECNKFEEGYHIHVVIGGPGLNPRNLTVCVEGLFNNVLYHLVTGNVKLKFLPGMTTKGKYFRDGEQFIENYLMKKIPLNVVWCVTNIDGYIDTCISATFRRGACHAKKPRMTTAINDTSSDAGEPSGTGAEVVPFNGKGTKASIKFQTMVNWLCENRVFTEDKWKLVDFNQYTLLSSSHSGSFQIQSALKLAIYKATNLVPTSTFLLHADFEQVMCIKDNKIVKLLLCQNYDPLLVGQHVLKWIDKKCGKKNTLWFYGPPSTGKTNLAMAIAKSVPVYGMVNWNNENFPFNDVAGKSLVVWDEGIIKSTIVEAAKAILGGQPTRVDQKMRGSVAVPGVPVVITSNGDITFVVSGNTTTTVHAKALKERMVKLNFTVRCSPDMGLLTEADVQQWLTWCNAQSWDHYENWAINYTFDFPGINADALHPDLQTTPIVTDTSISSSGGESSEELSESSFFNLITPGACNTETPRSSTPIPGTSSGESLVGSPVSSEVVAASWEE

Canonical Sequence ...

DNA #2 48 bases

Raw Sequence ...

(DA)(DA)(DG)(DA)(DA)(DG)(DA)(DC)(DA)(DC)(DC)(DA)(DA)(DA)(DT)(DC)(DA)(DG)(DA)(DT)(DG)(DC)(DC)(DG)(DC)(DC)(DG)(DG)(DT)(DC)(DG)(DC)(DC)(DG)(DC)(DC)(DG)(DG)(DT)(DA)(DG)(DG)(DC)(DG)(DG)(DG)(DA)(DC)

Canonical Sequence ...

AAGAAGACACCAAATCAGATGCCGCCGGTCGCCGCCGGTAGGCGGGAC

DNA #3 48 bases

Raw Sequence ...

(DG)(DT)(DC)(DC)(DC)(DG)(DC)(DC)(DT)(DA)(DC)(DC)(DG)(DG)(DC)(DG)(DG)(DC)(DG)(DA)(DC)(DC)(DG)(DG)(DC)(DG)(DG)(DC)(DC)(DC)(DC)(DC)(DC)(DC)(DC)(DC)(DC)(DC)(DC)(DC)(DC)(DC)(DC)(DC)(DC)(DC)(DC)(DC)

Canonical Sequence ...

GTCCCGCCTACCGGCGGCGACCGGCGGCCCCCCCCCCCCCCCCCCCCC

Non polymer #4 ANP

InChI=1S/C10H17N6O12P3/c11-8-5-9(13-2-12-8)16(3-14-5)10-7(18)6(17)4(27-10)1-26-31(24,25)28-30(22,23)15-29(19,20)21/h2-4,6-7,10,17-18H,1H2,(H,24,25)(H2,11,12,13)(H4,15,19,20,21,22,23)/t4-,6-,7-,10-/m1/s1

InChI=1S/C10H17N6O12P3/c11-8-5-9(13-2-12-8)16(3-14-5)10-7(18)6(17)4(27-10)1-26-31(24,25)28-30(22,23)15-29(19,20)21/h2-4,6-7,10,17-18H,1H2,(H,24,25)(H2,11,12,13)(H4,15,19,20,21,22,23)/t4-,6-,7-,10-/m1/s1

SMILES: c1nc(c2c(n1)n(cn2)[C@H]3[C@@H]([C@@H]([C@H](O3)CO[P@](=O)(O)O[P@@](=O)(NP(=O)(O)O)O)O)O)N

c1nc(c2c(n1)n(cn2)[C@H]3[C@@H]([C@@H]([C@H](O3)CO[P@](=O)(O)O[P@@](=O)(NP(=O)(O)O)O)O)O)N

Non polymer #5 MG

InChI=1S/Mg/q+2

SMILES: [Mg+2]

[Mg+2]

Biounit #1 hetero-12-1-1-mer

Reference