2025-06-14_00000267|medium|9NTK

Chimeric Adenosine deaminase growth factor (ADGF) in complex with pentostatin monophosphate; X-ray diffraction 2.53Å
Protein #1 536 residues (92% resolved)

MSSFSTHNFVAIATFVCWFCCLATAAPLTSKAAYLLKRNSLIEEDASRKLGAKIVLTNEEKVLDDFILAEKRKLIDDSRLNQTEYMPAASFYRSKDFIDTTFAYKIIQDMPKGGALHLHDTASARIDWIVSNATYRDHVYMCMDQDNFVRLTVSGTGPPANSGCEWKLVETERANSGDIAAFDHWLKSNISLLTTDPLVTYPSLDKVWGRFDKHFSQLRGIIYHTPIRRDYYRQILEEFRSDNVQYVEVRSSLSGFFELDGTVHDAEFGLNLYKSVTEEFQREYPDFIGAKIILSGLRFKSQEEILNEVKIAMDLHKKYPDFFLGYDLVGQEDPNFSLLHYLDALLYPSIQNPPYRLPYFFHAAETNWQETEVDYNLADALLLNTTRVGHGFALIKHPRFTELAKENGVAVEVNPISNQILGLVRDVRNHALVPLIADDYPIVISSDDPGAWEASPLSHDFYVALMDLCGRDTALTFLKQLALNSIRYSAMSDTEKVAAKAKWTTQWDKFVKTSVEGLKPHINDRSHHHHHHHHHH

MSSFSTHNFVAIATFVCWFCCLATAAPLTSKAAYLLKRNSLIEEDASRKLGAKIVLTNEEKVLDDFILAEKRKLIDDSRLNQTEYMPAASFYRSKDFIDTTFAYKIIQDMPKGGALHLHDTASARIDWIVSNATYRDHVYMCMDQDNFVRLTVSGTGPPANSGCEWKLVETERANSGDIAAFDHWLKSNISLLTTDPLVTYPSLDKVWGRFDKHFSQLRGIIYHTPIRRDYYRQILEEFRSDNVQYVEVRSSLSGFFELDGTVHDAEFGLNLYKSVTEEFQREYPDFIGAKIILSGLRFKSQEEILNEVKIAMDLHKKYPDFFLGYDLVGQEDPNFSLLHYLDALLYPSIQNPPYRLPYFFHAAETNWQETEVDYNLADALLLNTTRVGHGFALIKHPRFTELAKENGVAVEVNPISNQILGLVRDVRNHALVPLIADDYPIVISSDDPGAWEASPLSHDFYVALMDLCGRDTALTFLKQLALNSIRYSAMSDTEKVAAKAKWTTQWDKFVKTSVEGLKPHINDRSHHHHHHHHHH
Non polymer #2 A1CDW

InChI=1S/C11H17N4O7P/c16-6-1-9(22-8(6)3-21-23(18,19)20)15-5-14-10-7(17)2-12-4-13-11(10)15/h4-9,16-17H,1-3H2,(H,12,13)(H2,18,19,20)/t6-,7+,8+,9+/m0/s1

c1nc2c(n1[C@H]3C[C@@H]([C@H](O3)COP(=O)(O)O)O)N=CNC[C@H]2O
Non polymer #3 EDO

InChI=1S/C2H6O2/c3-1-2-4/h3-4H,1-2H2

C(CO)O
Non polymer #4 NAG

InChI=1S/C8H15NO6/c1-3(11)9-5-7(13)6(12)4(2-10)15-8(5)14/h4-8,10,12-14H,2H2,1H3,(H,9,11)/t4-,5-,6-,7-,8-/m1/s1

CC(=O)N[C@@H]1[C@H]([C@@H]([C@H](O[C@H]1O)CO)O)O
Non polymer #5 ZN

InChI=1S/Zn/q+2

[Zn+2]
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Reference