2025-05-10_00000130|ligand|9BS8

Structure of the SARS-CoV-2 main protease in complex with inhibitor YR-B-107; X-ray diffraction 1.70Å
Protein #1 306 residues (100% resolved)

SGFRKMAFPSGKVEGCMVQVTCGTTTLNGLWLDDVVYCPRHVICTSEDMLNPNYEDLLIRKSNHNFLVQAGNVQLRVIGHSMQNCVLKLKVDTANPKTPKYKFVRIQPGQTFSVLACYNGSPSGVYQCAMRPNFTIKGSFLNGSCGSVGFNIDYDCVSFCYMHHMELPTGVHAGTDLEGNFYGPFVDRQTAQAAGTDTTITVNVLAWLYAAVINGDRWFLNRFTTTLNDFNLVAMKYNYEPLTQDHVDILGPLSAQTGIAVLDMCASLKELLQNGMNGRTILGSALLEDEFTPFDVVRQCSGVTFQ

SGFRKMAFPSGKVEGCMVQVTCGTTTLNGLWLDDVVYCPRHVICTSEDMLNPNYEDLLIRKSNHNFLVQAGNVQLRVIGHSMQNCVLKLKVDTANPKTPKYKFVRIQPGQTFSVLACYNGSPSGVYQCAMRPNFTIKGSFLNGSCGSVGFNIDYDCVSFCYMHHMELPTGVHAGTDLEGNFYGPFVDRQTAQAAGTDTTITVNVLAWLYAAVINGDRWFLNRFTTTLNDFNLVAMKYNYEPLTQDHVDILGPLSAQTGIAVLDMCASLKELLQNGMNGRTILGSALLEDEFTPFDVVRQCSGVTFQ
Non polymer #2 A1AR4

InChI=1S/C23H31N3O5/c27-13-18(11-17-7-10-24-20(17)28)25-21(29)19-12-23(8-4-9-23)15-26(19)22(30)31-14-16-5-2-1-3-6-16/h1-3,5-6,17-19,27H,4,7-15H2,(H,24,28)(H,25,29)/t17-,18+,19-/m0/s1

c1ccc(cc1)COC(=O)N2CC3(CCC3)C[C@H]2C(=O)N[C@@H](C[C@@H]4CCNC4=O)CO
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Reference