2025-05-03_00000039|hard|9BNL

Cryo-EM structure of rhesus antibody 6070-a.01 in complex with HIV-1 Env trimer Q23.17 MD39; Electron microscopy 3.60Å

Protein #1 464 residues (95% resolved)

Raw Sequence ...

NLWVTVYYGVPVWRDADTTLFCASDAKAYETEKHNVWATHACVPTDPNPQEIHLDNVTEKFNMWKNNMVEQMHEDIISLWDQSLKPCVKLTPLCVTLHCTNVTSVNTTGDREGLKNCSFNMTTELRDKRQKVYSLFYRLDIVPINENQGSEYRLINCNTSAITQACPKVSFEPIPIHYCTPAGFAILKCKDEGFNGTGLCKNVSTVQCTHGIKPVVSTQLLLNGSLAEKNIIIRSENITNNAKIIIVQLVQPVTIKCIRPNNNTVKSIRIGPGQAFYYTGDIIGDIRQAHCNVTRSRWNKTLQEVAEKLRTYFGNKTIIFANSSGGDLEITTHSFNCGGEFFYCNTSGLFNSTWYVNSTWNDTDSTQESNDTITLPCRIKQIINMWQRAGQAMYAPPIPGVIKCESNITGLLLTRDGGKDNNVNETFRPGGSDMRDNWRSELYKYKVVEIEPLGVAPTRCKRRV

Canonical Sequence ...

Protein #2 142 residues (85% resolved)

Raw Sequence ...

LGFLGAAGSTMGAASITLTVQARNLLSGIVQQQNNLLRAIEAQQHLLKLTHWGIKQLQARVLAVEHYLRDQQLLGIWGCSGKLICCTNVPWNSSWSNKSLDEIWNNMTWLQWDKEINNYTQLIYRLIEESQNQQEKNEKELL

Canonical Sequence ...

LGFLGAAGSTMGAASITLTVQARNLLSGIVQQQNNLLRAIEAQQHLLKLTHWGIKQLQARVLAVEHYLRDQQLLGIWGCSGKLICCTNVPWNSSWSNKSLDEIWNNMTWLQWDKEINNYTQLIYRLIEESQNQQEKNEKELL

Protein #3 131 residues (100% resolved)

Raw Sequence ...

QVTLKESGPALVKPTQTLTLTCTFSGFSLSTSGMAVGWIRQPPGKALEWLANIYWDGDTYYSTSLKSRLTISKDTSKNQVALKMTNMDPVDTATYFCARGEESFYEDD(TYS)GQMEWLHSFDAWGQGLRVTVSS

Canonical Sequence ...

QVTLKESGPALVKPTQTLTLTCTFSGFSLSTSGMAVGWIRQPPGKALEWLANIYWDGDTYYSTSLKSRLTISKDTSKNQVALKMTNMDPVDTATYFCARGEESFYEDDYGQMEWLHSFDAWGQGLRVTVSS

Protein #4 107 residues (100% resolved)

Raw Sequence ...

DIQMTQSPPSLSASIGDRVTITCRASQGISNYLAWYQQKPGKAPKRLVYDASTLQGGVPSRFSGSGSGTYFSLTISSLQPEDFATYYCLQHNSHPLTFGGGTKVDIK

Canonical Sequence ...

DIQMTQSPPSLSASIGDRVTITCRASQGISNYLAWYQQKPGKAPKRLVYDASTLQGGVPSRFSGSGSGTYFSLTISSLQPEDFATYYCLQHNSHPLTFGGGTKVDIK

Non polymer #5 NAG

InChI=1S/C8H15NO6/c1-3(11)9-5-7(13)6(12)4(2-10)15-8(5)14/h4-8,10,12-14H,2H2,1H3,(H,9,11)/t4-,5-,6-,7-,8-/m1/s1

SMILES: CC(=O)N[C@@H]1[C@H]([C@@H]([C@H](O[C@H]1O)CO)O)O

CC(=O)N[C@@H]1[C@H]([C@@H]([C@H](O[C@H]1O)CO)O)O

Biounit #1 hetero-3-3-1-1-1-26-11-1-1-mer

Reference