2025-04-19_00000237|medium|9EYP

The structure of octameric pore of RN1 variant of actinoporin Fav; Electron microscopy 3.05Å

Protein #1 193 residues (94% resolved)

Raw Sequence ...

SELDSENDAADIAAGTIIAGAELTFGLLQNLLYFFANVNRKCAVGVDNESGFRWQEGSTYFFSGTADENLPYSVSDGYAVLYGPRKTNGPVATGVVGVLAYYIPSIGKTLAVMWSVPFDYNFYQNWWNAKLYSGNQRADYDHYVDLYYNANPFKANGWHERSLGSGLKFCGSMSSSGQATLEIHVLKESETCM

Canonical Sequence ...

SELDSENDAADIAAGTIIAGAELTFGLLQNLLYFFANVNRKCAVGVDNESGFRWQEGSTYFFSGTADENLPYSVSDGYAVLYGPRKTNGPVATGVVGVLAYYIPSIGKTLAVMWSVPFDYNFYQNWWNAKLYSGNQRADYDHYVDLYYNANPFKANGWHERSLGSGLKFCGSMSSSGQATLEIHVLKESETCM

Non polymer #2 A1H8M

InChI=1S/C41H83N2O6P/c1-6-8-10-12-14-16-18-20-21-23-25-27-29-31-33-35-41(45)42-39(38-49-50(46,47)48-37-36-43(3,4)5)40(44)34-32-30-28-26-24-22-19-17-15-13-11-9-7-2/h32,34,39-40,44H,6-31,33,35-38H2,1-5H3,(H-,42,45,46,47)/p+1/b34-32+/t39-,40+/m0/s1

InChI=1S/C41H83N2O6P/c1-6-8-10-12-14-16-18-20-21-23-25-27-29-31-33-35-41(45)42-39(38-49-50(46,47)48-37-36-43(3,4)5)40(44)34-32-30-28-26-24-22-19-17-15-13-11-9-7-2/h32,34,39-40,44H,6-31,33,35-38H2,1-5H3,(H-,42,45,46,47)/p+1/b34-32+/t39-,40+/m0/s1

SMILES: CCCCCCCCCCCCCCCCCC(=O)N[C@@H](COP(=O)(O)OCC[N+](C)(C)C)[C@@H](/C=C/CCCCCCCCCCCCC)O

CCCCCCCCCCCCCCCCCC(=O)N[C@@H](COP(=O)(O)OCC[N+](C)(C)C)[C@@H](/C=C/CCCCCCCCCCCCC)O

Biounit #1 homo-octamer

Reference