2025-03-29_00000272|hard|8ZUA

The complex structure of MPXV M1R and neutralizing antibody A138; X-ray diffraction 3.49Å

Protein #1 218 residues (100% resolved)

Raw Sequence ...

QVQLLESGGGLVKPGGSLRLSCAASGFTFRDYYMSWIREAPGKGLEWVASISRSGTTIYYADSVKGRFTISRDNAKNSLYLQMNSLRAEDTAVYYCARDEASSNYAFDYWGQGTPVTVSSASTKGPSVFPLAPSSKSTSGGTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKKV

Canonical Sequence ...

Protein #2 187 residues (89% resolved)

Raw Sequence ...

MGAAASIQTTVNTLSERISSKLEQEANASAQTKCDIEIGNFYIRQNHGCNITVKNMCSADADAQLDAVLSAATETYSGLTPEQKAYVPAMFTAALNIQTSVNTVVRDFENYVKQTCNSSAVVDNKLKIQNVIIDECYGAPGSPTNMEFINTGSSKGNCAIKALMQLTTKATTQIAPRQVAGHHHHHH

Canonical Sequence ...

MGAAASIQTTVNTLSERISSKLEQEANASAQTKCDIEIGNFYIRQNHGCNITVKNMCSADADAQLDAVLSAATETYSGLTPEQKAYVPAMFTAALNIQTSVNTVVRDFENYVKQTCNSSAVVDNKLKIQNVIIDECYGAPGSPTNMEFINTGSSKGNCAIKALMQLTTKATTQIAPRQVAGHHHHHH

Protein #3 213 residues (93% resolved)

Raw Sequence ...

IQLTQSPSSVSASVGDGVTITCRASQPIGTWVAWYQQKPGKAPKLLISGASSLQSGLPSRFSGRKSGTDFTLTISSLQPDDSATYFCQQTNTFPLTFGQGTRLEIKRTVAAPSVFIFPPSDEQLKSGTASVVCLLNNFYPREAKVQWKVDNALQSGNSQESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQGLSSPVTKSFNRGEC

Canonical Sequence ...

Biounit #1 hetero-1-1-1-mer

Biounit #2 hetero-1-1-1-mer

Biounit #3 hetero-1-1-1-mer

Biounit #4 hetero-1-1-1-mer

Reference