2025-03-29_00000134|ligand|7I5Y

Group deposition of Coxsackievirus A16 (G-10) 2A protease in complex with inhibitors from the ASAP AViDD centre -- Crystal structure of Coxsackievirus A16 (G-10) 2A protease in complex with ASAP-0036759-001 (A71EV2A-x4894); X-ray diffraction 1.84Å
Protein #1 144 residues (97% resolved)

SGAIYVGNYRVVNRHLATHNDWANLVWEDSSRDLLVSSTTAQGCDTIARCDCQTGVYYCSSRRKHYPVSFSKPSLIFVEASEYYPARYQSHLMLAVGHSEPGDCGGILRCQHGVVGIVSTGGNGLVGFADVRDLLWLDEEAMEQ

SGAIYVGNYRVVNRHLATHNDWANLVWEDSSRDLLVSSTTAQGCDTIARCDCQTGVYYCSSRRKHYPVSFSKPSLIFVEASEYYPARYQSHLMLAVGHSEPGDCGGILRCQHGVVGIVSTGGNGLVGFADVRDLLWLDEEAMEQ
Non polymer #2 A1B4P

InChI=1S/C15H20N2O3S/c1-21-12-6-3-2-5-11(12)9-13(18)17-8-4-7-15(20,10-17)14(16)19/h2-3,5-6,20H,4,7-10H2,1H3,(H2,16,19)/t15-/m1/s1

CSc1ccccc1CC(=O)N2CCC[C@@](C2)(C(=O)N)O
Non polymer #3 ZN

InChI=1S/Zn/q+2

[Zn+2]
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Reference