2025-03-29_00000090|ligand|7I4Q

Group deposition of Coxsackievirus A16 (G-10) 2A protease in complex with inhibitors from the ASAP AViDD centre -- Crystal structure of Coxsackievirus A16 (G-10) 2A protease in complex with ASAP-0036805-001 (A71EV2A-x4735); X-ray diffraction 1.22Å
Protein #1 144 residues (97% resolved)

SGAIYVGNYRVVNRHLATHNDWANLVWEDSSRDLLVSSTTAQGCDTIARCDCQTGVYYCSSRRKHYPVSFSKPSLIFVEASEYYPARYQSHLMLAVGHSEPGDCGGILRCQHGVVGIVSTGGNGLVGFADVRDLLWLDEEAMEQ

SGAIYVGNYRVVNRHLATHNDWANLVWEDSSRDLLVSSTTAQGCDTIARCDCQTGVYYCSSRRKHYPVSFSKPSLIFVEASEYYPARYQSHLMLAVGHSEPGDCGGILRCQHGVVGIVSTGGNGLVGFADVRDLLWLDEEAMEQ
Non polymer #2 A1B26

InChI=1S/C16H19N3OS/c1-21-15-7-3-2-5-12(15)9-16(20)19-8-4-6-14(19)13-10-17-11-18-13/h2-3,5,7,10-11,14H,4,6,8-9H2,1H3,(H,17,18)/t14-/m1/s1

CSc1ccccc1CC(=O)N2CCC[C@@H]2c3cnc[nH]3
Non polymer #3 DMS

InChI=1S/C2H6OS/c1-4(2)3/h1-2H3

CS(=O)C
Non polymer #4 ZN

InChI=1S/Zn/q+2

[Zn+2]
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Reference