2025-03-08_00000099|hard|8ZYS

Crystal structure of HSF5 DNA-binding domain in complex with 3-site HSE DNA (25 bp); X-ray diffraction 2.00Å

Protein #1 129 residues (74% resolved)

MHHHHHHPNNFPAKLWRLVNSPRYRSIRWDGRGEGLLIDQPLFEAELLSPPGPGGGGGTAGAGAEPELFKTTSFTSFIRQLNLYGFRKVVLGGPGGGKPAGNGPLHHFHNPHFRRDQPQLLVHLKRLTS

MHHHHHHPNNFPAKLWRLVNSPRYRSIRWDGRGEGLLIDQPLFEAELLSPPGPGGGGGTAGAGAEPELFKTTSFTSFIRQLNLYGFRKVVLGGPGGGKPAGNGPLHHFHNPHFRRDQPQLLVHLKRLTS

DNA #2 25 bases

(DA)(DC)(DT)(DC)(DG)(DC)(DG)(DA)(DA)(DT)(DA)(DT)(DT)(DC)(DT)(DA)(DG)(DA)(DA)(DC)(DG)(DC)(DG)(DA)(DC)

ACTCGCGAATATTCTAGAACGCGAC

DNA #3 25 bases

(DT)(DG)(DT)(DC)(DG)(DC)(DG)(DT)(DT)(DC)(DT)(DA)(DG)(DA)(DA)(DT)(DA)(DT)(DT)(DC)(DG)(DC)(DG)(DA)(DG)

TGTCGCGTTCTAGAATATTCGCGAG

Biounit #1 hetero-3-1-1-mer

Biounit #2 hetero-3-1-1-mer

Reference