2025-03-08_00000002|medium|8Q67

Crystal structure of a homohexameric MCM from M. acidophilum; X-ray diffraction 2.59Å
Protein #1 601 residues (97% resolved)

GMAEQQTSSLKLLFDEFLESYYSDEIKDIIIKFPNKRSLPVNISDLEEFDPDTATNLIADPEIIIDAANESLMGKLAGLNFDTYIPHVRFYNQSINTPMVLNVGSAYINKFVSIDALVVKRSDIRPKIRDAVFVCTFCNAKVKANLEKEEIPKVCPECKKRTLKIVPEESSFFNSQKIAVQDPLERLSGSIPTWQLEAWLDDDLVNMAIPGDRIEISGVLKIRPRKDSRGKVDPSIYSMYLNVTSLETKQKEFADIDISEDEERQIKELSKDPEIFNKVTQSVAPSIYGYNEIKQAVALQLFGGTPGKKLVDGGQIRSDMHILLIGDPGSAKTRILQSVSRLVPKGIYVSGKSVTGGGLTAVAERDDFSEGGWTLKAGAMVLGNGGIVAIDQFDKISEEDTAALHEALESQTISVAKAGIIATFNAKASVLAAANPKFGRFDPHKYPAEQFDISPTLLSRFDLIFPIRDIMDTELDKSIANYILNQHEAAGAAIADVESSVAAEEPPIEHSLLKKYIAYAKRYVMPRLSEEASNRIKEYYVDLRRAGSMKGATPITPRQIEGLIRMAEASAKSQLRDVVSVKDANLAISLSEYMLKTLAVD

GMAEQQTSSLKLLFDEFLESYYSDEIKDIIIKFPNKRSLPVNISDLEEFDPDTATNLIADPEIIIDAANESLMGKLAGLNFDTYIPHVRFYNQSINTPMVLNVGSAYINKFVSIDALVVKRSDIRPKIRDAVFVCTFCNAKVKANLEKEEIPKVCPECKKRTLKIVPEESSFFNSQKIAVQDPLERLSGSIPTWQLEAWLDDDLVNMAIPGDRIEISGVLKIRPRKDSRGKVDPSIYSMYLNVTSLETKQKEFADIDISEDEERQIKELSKDPEIFNKVTQSVAPSIYGYNEIKQAVALQLFGGTPGKKLVDGGQIRSDMHILLIGDPGSAKTRILQSVSRLVPKGIYVSGKSVTGGGLTAVAERDDFSEGGWTLKAGAMVLGNGGIVAIDQFDKISEEDTAALHEALESQTISVAKAGIIATFNAKASVLAAANPKFGRFDPHKYPAEQFDISPTLLSRFDLIFPIRDIMDTELDKSIANYILNQHEAAGAAIADVESSVAAEEPPIEHSLLKKYIAYAKRYVMPRLSEEASNRIKEYYVDLRRAGSMKGATPITPRQIEGLIRMAEASAKSQLRDVVSVKDANLAISLSEYMLKTLAVD
Non polymer #2 ADP

InChI=1S/C10H15N5O10P2/c11-8-5-9(13-2-12-8)15(3-14-5)10-7(17)6(16)4(24-10)1-23-27(21,22)25-26(18,19)20/h2-4,6-7,10,16-17H,1H2,(H,21,22)(H2,11,12,13)(H2,18,19,20)/t4-,6-,7-,10-/m1/s1

c1nc(c2c(n1)n(cn2)[C@H]3[C@@H]([C@@H]([C@H](O3)CO[P@](=O)(O)OP(=O)(O)O)O)O)N
Non polymer #3 PO4

InChI=1S/H3O4P/c1-5(2,3)4/h(H3,1,2,3,4)/p-3

[O-]P(=O)([O-])[O-]
Non polymer #4 ZN

InChI=1S/Zn/q+2

[Zn+2]
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Reference