2025-02-22_00000169|ligand|7HXY

Group deposition of Coxsackievirus A16 (G-10) 2A protease in complex with inhibitors from the ASAP AViDD centre -- Crystal structure of Coxsackievirus A16 (G-10) 2A protease in complex with ASAP-0035366-001 (A71EV2A-x4319); X-ray diffraction 1.69Å
Protein #1 144 residues (97% resolved)

SGAIYVGNYRVVNRHLATHNDWANLVWEDSSRDLLVSSTTAQGCDTIARCDCQTGVYYCSSRRKHYPVSFSKPSLIFVEASEYYPARYQSHLMLAVGHSEPGDCGGILRCQHGVVGIVSTGGNGLVGFADVRDLLWLDEEAMEQ

SGAIYVGNYRVVNRHLATHNDWANLVWEDSSRDLLVSSTTAQGCDTIARCDCQTGVYYCSSRRKHYPVSFSKPSLIFVEASEYYPARYQSHLMLAVGHSEPGDCGGILRCQHGVVGIVSTGGNGLVGFADVRDLLWLDEEAMEQ
Non polymer #2 A1BS1

InChI=1S/C15H18F2N2O3/c16-15(17)22-12-6-2-1-4-10(12)8-13(20)19-7-3-5-11(9-19)14(18)21/h1-2,4,6,11,15H,3,5,7-9H2,(H2,18,21)/t11-/m0/s1

c1ccc(c(c1)CC(=O)N2CCC[C@@H](C2)C(=O)N)OC(F)F
Non polymer #3 DMS

InChI=1S/C2H6OS/c1-4(2)3/h1-2H3

CS(=O)C
Non polymer #4 ZN

InChI=1S/Zn/q+2

[Zn+2]
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Reference