2024-11-09_00000090|medium|8XHM

Crystal structure of Nocardia seriolae dUTP diphosphatase; X-ray diffraction 2.12Å

Protein #1 194 residues (72% resolved)

Raw Sequence ...

MTGIPPIPLLRLDPGIPVPVRAHEGDAGVDLCTTEDVIIEPGERVLVGTGIAVALPIGTVGLIHPRSGLAAKAGLSVVNTPGTVDAGYRGEIKVCLINHDPRAAIELRRGDRIAQLLVQKVELVDFVEVETLDETARGAGGYGSSGGHASLAAQSGGAGQATGKEAGGGGSLEVLFQGPGGGGSLEVDHHHHHH

Canonical Sequence ...

MTGIPPIPLLRLDPGIPVPVRAHEGDAGVDLCTTEDVIIEPGERVLVGTGIAVALPIGTVGLIHPRSGLAAKAGLSVVNTPGTVDAGYRGEIKVCLINHDPRAAIELRRGDRIAQLLVQKVELVDFVEVETLDETARGAGGYGSSGGHASLAAQSGGAGQATGKEAGGGGSLEVLFQGPGGGGSLEVDHHHHHH

Non polymer #2 PEG

InChI=1S/C4H10O3/c5-1-3-7-4-2-6/h5-6H,1-4H2

SMILES: C(COCCO)O

C(COCCO)O

Non polymer #3 PO4

InChI=1S/H3O4P/c1-5(2,3)4/h(H3,1,2,3,4)/p-3

SMILES: [O-]P(=O)([O-])[O-]

[O-]P(=O)([O-])[O-]

Non polymer #4 TRS

InChI=1S/C4H11NO3/c5-4(1-6,2-7)3-8/h6-8H,1-3,5H2/p+1

SMILES: C(C(CO)(CO)[NH3+])O

C(C(CO)(CO)[NH3+])O

Non polymer #5 UMP

InChI=1S/C9H13N2O8P/c12-5-3-8(11-2-1-7(13)10-9(11)14)19-6(5)4-18-20(15,16)17/h1-2,5-6,8,12H,3-4H2,(H,10,13,14)(H2,15,16,17)/t5-,6+,8+/m0/s1

SMILES: C1[C@@H]([C@H](O[C@H]1N2C=CC(=O)NC2=O)COP(=O)(O)O)O

C1[C@@H]([C@H](O[C@H]1N2C=CC(=O)NC2=O)COP(=O)(O)O)O

Biounit #1 homo-trimer

Reference