2024-10-12_00000090|ligand|8ROV

Human dectin-2 with dimerization domain; X-ray diffraction 2.36Å

Protein #1 193 residues (75% resolved)

Raw Sequence ...

MANEIAALKQEIAALKKENAALKQGKLHFTYGETGKRLSELHSYHSSLTCFSEGTKVPAWGCCPASWKSFGSSCYFISSEEKVWSKSEQNCVEMGAHLVVFNTEAEQNFIVQQLNESFSYFLGLSDPQGNNNWQWIDKTPYEKNVRFWHLGEPNHSAEQCASIVFWKPTGWGWNDVICETRRNSICEMNKIYL

Canonical Sequence ...

MANEIAALKQEIAALKKENAALKQGKLHFTYGETGKRLSELHSYHSSLTCFSEGTKVPAWGCCPASWKSFGSSCYFISSEEKVWSKSEQNCVEMGAHLVVFNTEAEQNFIVQQLNESFSYFLGLSDPQGNNNWQWIDKTPYEKNVRFWHLGEPNHSAEQCASIVFWKPTGWGWNDVICETRRNSICEMNKIYL

Non polymer #2 CA

InChI=1S/Ca/q+2

SMILES: [Ca+2]

[Ca+2]

Non polymer #3 MMA

InChI=1S/C7H14O6/c1-12-7-6(11)5(10)4(9)3(2-8)13-7/h3-11H,2H2,1H3/t3-,4-,5+,6+,7+/m1/s1

SMILES: CO[C@@H]1[C@H]([C@H]([C@@H]([C@H](O1)CO)O)O)O

CO[C@@H]1[C@H]([C@H]([C@@H]([C@H](O1)CO)O)O)O

Non polymer #4 NA

InChI=1S/Na/q+1

SMILES: [Na+]

[Na+]

Biounit #1 homo-dimer

Reference