2024-08-17_00000031|hard|8Q56

Phage defense complex; X-ray diffraction 3.50Å
Protein #1 1225 residues (99% resolved)

MNTNNIKKYAPQARNQFRDAVIQKLTTLGISADKKGNLQIADAELVGETMRYGQFDYPKSTLTRRDRLVKRAREQGFDVLVEHCAYTWFNRLCAIRYMEIHGYLDHGFHMLSHPDNPTGFEVLDHVPEVAEALLPEKKAQLVEMKLSGNQDEAIYRELLLAQCHALHRAMPFLFEAVDDEAELLLPDNLTRTDSILRGLVDGIPEEDWQEVEVIGWLYQFYISEKKDAVIGKVVKSEDIPAATQLFTPNWIVQYLVQNSVGRQWLQTYPDSPLKGKMDYYIEPAEQTPEVQAQLAAITPASIEPESIKVLDPACGSGHILIEVYNVLKNIYEERGYRARDIPQLILENNIFGLDIDDRAAQLSGFALLMMARQDDRRIFTRDVRLNIVSLQESLHLDIAKLWQQLNFHQQNQTGSMGDMFAENTALAHTDSAEYQLLMRTLKRFVNAKTLGSLIQVPQEEEAELKAFLEALYRMEQEGDFQQKAAAKAFIPYIQQAWILAQRYDAVVANPPYMGGKGMNSELKEFAKNNFPDSKADLFAMFMQNAFSLLKENGFNAQVNMQSWMFLSSYEALRNWLLDNKTFITMAHLGARAFGQISGEVVQTTAWVIKNQHSERYQPVFFRLIDGREEVKKSDLLLRKNIFDKFTQHDFKNIPGMPIAYWIDLPSLLSFRHHKKLGEKIALKAGMSTGDNIKFQRYWYEVSIKKTLITNKESNTKIDIHNIKWFPCSSGGEYRKWYGNNEIVVNWENNGYEIRNFKFENGKTRSAVRNDEYYFREGITWSKISQGNFCVRYRPKGFVFDDTGRCGFSNNKNELLYAAGLMCTPVVNHYLSILAPTLSFTSGELASVPYPEIEDEIIELVTNAIEIAKNDWDSQEQSWDYVCSPLLEHNSTQLLRNIYKQKINTNIKLVETLLLIENTINNIFIDKLQLDKTIIKAVLQSEITLLCNPNYRYKNIQDHTDLTNKYYTDITIDILSYIIGCMMGRYSLDREGLVYAHEGNKGFAELVAEDAYKTFPADNDGILPLMDDEWFDDDVTSRVKEFVRTVWGEEHLQENLEFIAESLCLYAIKPKKGESALDTIRRYLSTQFWKDHMKMYKKRPIYWLFSSGKEKAFECLVYLHRYNDATLARMRTEYVVPLLARYQANIDRLNEQVDGASGGEATRLKRERDSLSKKFNELRSFDDRLRHYADMRISIDLDDGVKVNYGKFGDLLADVKAITGNAPEII

MNTNNIKKYAPQARNQFRDAVIQKLTTLGISADKKGNLQIADAELVGETMRYGQFDYPKSTLTRRDRLVKRAREQGFDVLVEHCAYTWFNRLCAIRYMEIHGYLDHGFHMLSHPDNPTGFEVLDHVPEVAEALLPEKKAQLVEMKLSGNQDEAIYRELLLAQCHALHRAMPFLFEAVDDEAELLLPDNLTRTDSILRGLVDGIPEEDWQEVEVIGWLYQFYISEKKDAVIGKVVKSEDIPAATQLFTPNWIVQYLVQNSVGRQWLQTYPDSPLKGKMDYYIEPAEQTPEVQAQLAAITPASIEPESIKVLDPACGSGHILIEVYNVLKNIYEERGYRARDIPQLILENNIFGLDIDDRAAQLSGFALLMMARQDDRRIFTRDVRLNIVSLQESLHLDIAKLWQQLNFHQQNQTGSMGDMFAENTALAHTDSAEYQLLMRTLKRFVNAKTLGSLIQVPQEEEAELKAFLEALYRMEQEGDFQQKAAAKAFIPYIQQAWILAQRYDAVVANPPYMGGKGMNSELKEFAKNNFPDSKADLFAMFMQNAFSLLKENGFNAQVNMQSWMFLSSYEALRNWLLDNKTFITMAHLGARAFGQISGEVVQTTAWVIKNQHSERYQPVFFRLIDGREEVKKSDLLLRKNIFDKFTQHDFKNIPGMPIAYWIDLPSLLSFRHHKKLGEKIALKAGMSTGDNIKFQRYWYEVSIKKTLITNKESNTKIDIHNIKWFPCSSGGEYRKWYGNNEIVVNWENNGYEIRNFKFENGKTRSAVRNDEYYFREGITWSKISQGNFCVRYRPKGFVFDDTGRCGFSNNKNELLYAAGLMCTPVVNHYLSILAPTLSFTSGELASVPYPEIEDEIIELVTNAIEIAKNDWDSQEQSWDYVCSPLLEHNSTQLLRNIYKQKINTNIKLVETLLLIENTINNIFIDKLQLDKTIIKAVLQSEITLLCNPNYRYKNIQDHTDLTNKYYTDITIDILSYIIGCMMGRYSLDREGLVYAHEGNKGFAELVAEDAYKTFPADNDGILPLMDDEWFDDDVTSRVKEFVRTVWGEEHLQENLEFIAESLCLYAIKPKKGESALDTIRRYLSTQFWKDHMKMYKKRPIYWLFSSGKEKAFECLVYLHRYNDATLARMRTEYVVPLLARYQANIDRLNEQVDGASGGEATRLKRERDSLSKKFNELRSFDDRLRHYADMRISIDLDDGVKVNYGKFGDLLADVKAITGNAPEII
Protein #2 117 residues (92% resolved)

MAMSNMTYNNVFDHAYEMLKENIRYDDIRDTDDLHDAIHMAADNAVPHYYADIFSVMASEGIDLEFEDSGLMPDTKDVIRILQARIYEQLTIDLWEDAEDLLNEYLEEVEEYEEDEE

MAMSNMTYNNVFDHAYEMLKENIRYDDIRDTDDLHDAIHMAADNAVPHYYADIFSVMASEGIDLEFEDSGLMPDTKDVIRILQARIYEQLTIDLWEDAEDLLNEYLEEVEEYEEDEE
Non polymer #3 SAM

InChI=1S/C15H22N6O5S/c1-27(3-2-7(16)15(24)25)4-8-10(22)11(23)14(26-8)21-6-20-9-12(17)18-5-19-13(9)21/h5-8,10-11,14,22-23H,2-4,16H2,1H3,(H2-,17,18,19,24,25)/t7-,8+,10+,11+,14+,27-/m0/s1

C[S@@+](CC[C@@H](C(=O)[O-])N)C[C@@H]1[C@H]([C@H]([C@@H](O1)n2cnc3c2ncnc3N)O)O
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Reference