2024-07-27_00000089|medium|8TJS

CRYO-EM STRUCTURE OF HIV-1 BG505DS-SOSIP.664 ENV TRIMER BOUND TO GPZ6-a.01 FAB; Electron microscopy 3.31Å

Protein #1 480 residues (94% resolved)

Raw Sequence ...

AENLWVTVYYGVPVWKDAETTLFCASDAKAYETEKHNVWATHACVPTDPNPQEIHLENVTEEFNMWKNNMVEQMHTDIISLWDQSLKPCVKLTPLCVTLQCTNVTNNITDDMRGELKNCSFNMTTELRDKKQKVYSLFYRLDVVQINENQGNRSNNSNKEYRLINCNTSACTQACPKVSFEPIPIHYCAPAGFAILKCKDKKFNGTGPCPSVSTVQCTHGIKPVVSTQLLLNGSLAEEEVMIRSENITNNAKNILVQFNTPVQINCTRPNNNTRKSIRIGPGQAFYATGDIIGDIRQAHCNVSKATWNETLGKVVKQLRKHFGNNTIIRFANSSGGDLEVTTHSFNCGGEFFYCNTSGLFNSTWISNTSVQGSNSTGSNDSITLPCRIKQIINMWQRIGQCMYAPPIQGVIRCVSNITGLILTRDGGSTNSTTETFRPGGGDMRDNWRSELYKYKVVKIEPLGVAPTRCKRRVGRRRRRR

Canonical Sequence ...

Protein #2 153 residues (86% resolved)

Raw Sequence ...

AVGIGAVFLGFLGAAGSTMGAASMTLTVQARNLLSGIVQQQSNLLRAPEAQQHLLKLTVWGIKQLQARVLAVERYLRDQQLLGIWGCSGKLICCTNVPWNSSWSNRNLSEIWDNMTWLQWDKEISNYTQIIYGLLEESQNQQEKNEQDLLALD

Canonical Sequence ...

AVGIGAVFLGFLGAAGSTMGAASMTLTVQARNLLSGIVQQQSNLLRAPEAQQHLLKLTVWGIKQLQARVLAVERYLRDQQLLGIWGCSGKLICCTNVPWNSSWSNRNLSEIWDNMTWLQWDKEISNYTQIIYGLLEESQNQQEKNEQDLLALD

Protein #3 126 residues (99% resolved)

Raw Sequence ...

EAHLVESGGGLTQPGGSLRLSCVVSGISFSGHYMHWVRLSSGRGLEWVSGISDIGDKRWYADSVRGRFTISRENAKNTLYLQMDNLRPEDSAVYYCTGRAILYPRAYYKDHRSDVWGAGVLVTVSS

Canonical Sequence ...

EAHLVESGGGLTQPGGSLRLSCVVSGISFSGHYMHWVRLSSGRGLEWVSGISDIGDKRWYADSVRGRFTISRENAKNTLYLQMDNLRPEDSAVYYCTGRAILYPRAYYKDHRSDVWGAGVLVTVSS

Protein #4 107 residues (100% resolved)

Raw Sequence ...

EIVMTQSPATLSVSPGERATLSCRASQSVASDLVWYQQKPGQPPRVLIYEASKRAAGCPDRFSGSGSGTDFTLNINSLEPEDVGVYYCQQEIDWPLTFGGGTTVEIK

Canonical Sequence ...

EIVMTQSPATLSVSPGERATLSCRASQSVASDLVWYQQKPGQPPRVLIYEASKRAAGCPDRFSGSGSGTDFTLNINSLEPEDVGVYYCQQEIDWPLTFGGGTTVEIK

Non polymer #5 NAG

InChI=1S/C8H15NO6/c1-3(11)9-5-7(13)6(12)4(2-10)15-8(5)14/h4-8,10,12-14H,2H2,1H3,(H,9,11)/t4-,5-,6-,7-,8-/m1/s1

SMILES: CC(=O)N[C@@H]1[C@H]([C@@H]([C@H](O[C@H]1O)CO)O)O

CC(=O)N[C@@H]1[C@H]([C@@H]([C@H](O[C@H]1O)CO)O)O

Biounit #1 hetero-3-3-3-3-3-6-mer

Reference