2024-05-18_00000131|medium|8STL

Crystal Structure of Nanobody PIK3_Nb16 against wild-type PI3Kalpha; X-ray diffraction 1.85Å

Protein #1 141 residues (88% resolved)

MAQVQLQESGGGLVQAGGSLKLSCTASGLRVDTHGMGWFRQIARKKREFVASIDWEGESTNYLDSVKGRFIISRDDAKNTLYLQMNSLKPEDTAVYYCAADRSGRIRSVVSNNDYWGQGTQVTVSSGRYPYDVPDYGSGRA

MAQVQLQESGGGLVQAGGSLKLSCTASGLRVDTHGMGWFRQIARKKREFVASIDWEGESTNYLDSVKGRFIISRDDAKNTLYLQMNSLKPEDTAVYYCAADRSGRIRSVVSNNDYWGQGTQVTVSSGRYPYDVPDYGSGRA

Biounit #1 monomer

Biounit #2 monomer

Biounit #3 monomer

Biounit #4 monomer

Reference