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CAMEO continuously evaluate the accuracy and reliability of predictions

  • 3D - Protein Stucture 140 weeks, 2352 targets, 28 registered servers.

  • LB - Ligand Binding Site 140 weeks, 6069 targets (I: 2877, O: 4421, N: 380, P: 222), 12 registered servers.

  • QE - Model Quality Estimation 30 weeks, 3090 targets (Low: 481, Medium: 2046, High: 563), 12 registered participants (servers or standalone software).

Predictions in all categories are evaluated against reference structures released by the PDB on a weekly basis.

  • CAMEO is a community project

    • CAMEO continuously applies quality assessment criteria established by the protein structure prediction community. Since the accuracy requirements for different scientific applications vary, there is no "one fits all" score. CAMEO therefore offers a variety of scores - assessing different aspects of a prediction (coverage, local accuracy, completeness, etc.) to reflect these requirements.
    • CAMEO is a community project - please feel free to suggest additional/alternative ways how CAMEO can support users and developers of structure prediction.
  • Join CAMEO today... We invite developers of prediction methods to participate in the continuous evaluation by registering their servers [REGISTER]. We also invite developers of scoring and evaluation methods to suggest alternative scoring schemes. Please contact us directly.

    Servers of the following groups are registered so far:
    A. Sali, L. McGuffin, T. Schwede, J. Soeding, D. Baker, A. Fiser, M. Sternberg, Y. Zhang, C. Floudas, S. Tosatto, J. Xu, Y. Zhou and O. Brock.

CAMEO is developed by the Computational Structural Biology Group at the Swiss Institute of Bioinformatics (SIB) and the Biozentrum of the University of Basel. CAMEO is partially supported by the SIB Swiss Institute of Bioinformatics and by grant U01 GM093324-01 from the National Institute of General Medical Sciences.